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- Brand: Clofi-25 / Clofi-50 / Clofi-100
- Composition: Clomiphene Citrate
- Power: 25mg, 50mg, 100mg
- Treatment: Infertility, Oligospermia, Androgen Deficiency
- Manufacturer: Sunrise Remedies Pvt. Ltd.
- Country of Origin: India
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Clofi® 25 / 50 / 100 mg (Clomiphene/Clomifene citrate) is a drug for the treatment of infertility in women and men, it is also used to diagnose disorders of the gonadotropic function of the pituitary gland.
- Clomiphene belongs to antiestrogenic agents, selectively blocks the receptor binding of estradiol in the ovaries and hypothalamus. This leads to the suppression of negative feedback, stimulates ovulation and the production of gonadotropins.
- Clofi® 25 / 50 / 100 mg has a moderate estrogenic effect when using low doses of the drug, increases the secretion of gonadotropins, stimulates ovulation.
- When using high doses, the drug Clofi® 25 / 50 / 100 mg exhibits an anti-estrogenic effect, inhibits the production of gonadotropins https://tadasiva.com.
Clofi® 25 / 50 / 100 mg Testosterone
Clofi® Clomiphene Citrate is a SERM that is specifically used as a fertility aid due to its ability to increase the release of gonadotropins. Clofi® has the ability to counteract the negative feedback of estrogens on the hypothalamus-pituitary-ovary axis. This will significantly increase the release of luteinizing hormone (LH) and follicle stimulating hormone (FSH). By increasing the release of gonadotropin, this can lead to the release of an egg, thereby increasing the likelihood of conception.
Clofi® it also has strong anti-estrogenic properties that can be used for therapeutic purposes, but its anti-estrogenic properties are most often associated with the use of anabolic steroids. Testosterone and many steroids derived from testosterone have the ability to convert into estrogen due to the interaction of testosterone with the aromatase enzyme. An increase in estrogen levels can lead to gynecomastia and water retention. Water retention in the body can also contribute to an increase in blood pressure. By adding Clofi® during the use of anabolic steroids, SERM will bind to estrogen receptors, thereby preventing the binding of the hormone estrogen. This can be very useful in the fight against gynecomastia, because when clomid binds to the receptor, it prevents estrogen stimulation of breast tissue. It can also have a positive effect on water retention,
Clofi® it also has functional characteristics that are useful for anabolic steroid users after using anabolic steroids. In particular, we are referring to post-course therapy (PCT). In men, Clofi® it also has the ability to stimulate the pituitary gland to produce more LH and FSH, which, in turn, stimulates increased natural testosterone production. This is extremely useful for those who take anabolic steroids after the course, as the natural testosterone level will be very low due to the suppression caused by the use of anabolic steroids.
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Clofi® 25 / 50 / 100 mg for men
The use of Clofi® for men is indicated for several months under strict systematic control of the spermogram. Clofi® has proven to be effective for stimulating the production of gonadotropins, but does not exhibit properties in gynecomastia in breast tissues.
As an antiestrogen when using steroids during the course, clomid is quite effective in preventing gynecomastia. Clofi® does not reduce estrogen levels and does not inhibit the aromatization process, but in many cases binding to receptors is sufficient protection for many men. In fact, even though stronger protective agents exist, many men would be surprised how well a SERM like Clofi® could work if they gave it a chance.
More importantly, using Clofi® for this purpose can also have a positive effect on cholesterol levels. Although Clofi® is an antiestrogen, it actually acts as an estrogen in the liver, which in turn contributes to healthier cholesterol levels. This can be very beneficial for the anabolic steroid user, as the use of anabolic steroids is known to increase unhealthy cholesterol levels.
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Clofi® 25 / 50 / 100 mg for women
Clofi® is an oral medication that is often used to treat certain types of female infertility.
Clofi® is often prescribed to women with polycystic ovary syndrome or PCOS, which is a syndrome that can cause irregular or absent ovulation.
Clofi® works by making the body think that estrogen levels are lower than they are, which causes the pituitary gland to increase the secretion of follicle-stimulating hormone, or FSH, and luteinizing hormone, or LH. Higher levels of FSH stimulate the ovaries to form an egg follicle or multiple follicles that will develop and be released during ovulation. High levels of LH stimulate ovulation.
Clofi® is often prescribed by primary care physicians or OB-GYN before they refer a couple to see a fertility specialist for more specialized care. specialists also prescribe Clofi®.
Doctors usually prescribe one, two, three, and sometimes four pills to be taken at the same time every day, depending on how they think you will respond to the medication. It usually starts with the lowest dose and increases every month as needed.
Some doctors will want you to go back to blood work to measure hormone levels or a transvaginal ultrasound to look at your ovarian follicles. This information can help them determine when you should start sexual intercourse or have intrauterine insemination. It can also help them determine the appropriate dose for the next cycle.
Most doctors do not recommend using Clofi® for more than three to six cycles due to a decrease in the frequency of pregnancy that occurs with continued use. Your doctor may extend this if it takes several cycles before they find a dose that works for you.
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Clofi® 25 / 50 / 100 mg dosage
The instructions on Clofi® indicate how to take the drug, recommending a dose for the first course of treatment of 50 mg daily for five days, starting from the fifth day of the menstrual cycle. In the absence of ovulation, there is no need to increase the dosage during subsequent courses of treatment.
Next, a second course of treatment is prescribed (not earlier than a month after the end of the first) at a dosage of Clofi® 100 mg daily for a period of 5 days.
During the third course, it is recommended to take Clofi® 100 mg daily for a period of 5 days; there should be no increase in the dose or duration of therapy, as during the second course.
The most complete course of therapy for most patients is 3 cycles. If there is no effect from the reception, further treatment is impractical.
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Overdose of Clofi®
There are no reports of such cases.
Interaction of Clofi® with medicinal products
There is no data on clinically significant interactions with other drugs.
Clofi® 25 / 50 / 100 mg side effects
Clofi® can cause drowsiness, dizziness, depression, insomnia, increased excitability and headache. Nausea, diarrhea, vomiting, and gastralgia may occur when taking Clofi®. Allergic manifestations rarely appear: allergic dermatitis, vasomotor disorders. When treated with the drug, it is possible to increase body weight, soreness in the mammary glands, decreased visual acuity, abdominal pain, menorrhagia, an increase in the size of the ovary and other disorders. When using Clofi®, the risk of blood clots may increase.
When treated with Clofi®, multiple pregnancies may develop. It should be borne in mind that the effectiveness of the drug increases with a normal level of endogenous estrogens, with a low level of estrogens it is ineffective, and with insufficiency of pituitary gonadotropins it is practically not effective. During the treatment of female infertility, there should be monitoring of the condition of the ovaries, their functionality.
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Clofi® 25 / 50 / 100 mg success rate
Clofi® is an excellent SERM, and for many years there has been a debate among anabolic steroid users about which SERM is better, Clofi® or Nolvadex. In order to protect against gynecomastia during the cycle, anyone will do. Most of those who use Clofi® do not use it enough. Study and understand SERM and the various elements before using them.
The use of Clofi® increases the likelihood of multiple pregnancies. Clofi® is effective with a sufficient concentration of endogenous estrogens, with a low concentration of estrogens it is less effective and almost ineffective with a low content of pituitary gonadotropins.
In the course of therapy, regular supervision of a gynecologist is necessary, it is necessary to monitor the work of the ovaries, examination of the vagina. You also need to be careful when driving.
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Application of the drug Clofi® 25 / 50 / 100 mg
Clofi® is used to treat infertility in women and men:
- Anovulatory infertility
- Dysgonadotropic form of amenorrhea
- Dysfunctional metrorrhagia
- Pituitary tumor that developed against this background galactorrhea
- Stein-Leventhal syndrome
- Chiari-Frommel syndrome
- Androgen deficiency
Where can I keep Clofi® 25 / 50 / 100 mg?
Keep out of the reach of children.
Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F). Protect from heat, light, and moisture. Throw away any unused medicine after the expiration date.
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